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Literature summary extracted from

  • Kang, S.; Kim, B.; Heo, K.; Jang, J.; Kim, W.; Hong, Y.
    Production of bacterial quorum sensing antagonists, caffeoyl- and Feruloyl-HSL, by an artificial biosynthetic pathway (2017), J. Microbiol. Biotechnol., 27, 2104-2111.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.229 synthesis production of bacterial quorum sensing antagonists, caffeoyl- and Feruloyl-HSL, by an artificial biosynthetic pathway. An Escherichia coli system containing artificial biosynthetic pathways that yield phenylacetyl-homoserine lactones from simple carbon sources. The artificial biosynthetic pathways contain the LuxI-type synthase gene (rpaI) in addition to caffeoyl-CoA and feruloyl-CoA biosynthetic genes, respectively. The yields for caffeoyl-phenylacetyl-homoserine lactone and feruloyl-phenylacetyl-homoserine lactone are 97.1 and 65.2 mg/l, respectively, by tyrosine-overproducing Escherichia coli with a L-methionine feeding strategy Rhodopseudomonas palustris

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.229 engineered biosynthetic pathways for the phenylacetyl-homoserine lactones analogs in Escherichia coli with N-acyl-homoserine lactone synthase (RpaI) from Rhodopseudomonas palustris, tyrosine ammonia lyase (TAL) from Saccharothrix espanaensis, coumarate 3-hydroxylase (Sam5) from S. espanaensis, caffeic acid O-methyltransferase (COM) from Arabidopsis thaliana, and p-coumarate-CoA ligase (4CL) from Nicotiana tabacum Rhodopseudomonas palustris

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.229 Rhodopseudomonas palustris Q6NCZ6
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-
2.3.1.229 Rhodopseudomonas palustris ATCC BAA-98 Q6NCZ6
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-

Synonyms

EC Number Synonyms Comment Organism
2.3.1.229 pcoumaroyl-HSL synthase
-
 Rhodopseudomonas palustris
2.3.1.229 RpaI
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 Rhodopseudomonas palustris