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Literature summary for 7.6.2.9 extracted from
- A glycine betaine importer limits Salmonella stress resistance and tissue colonization by reducing trehalose production (2012), Mol. Microbiol., 84, 296-309.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Salmonella enterica | - |
- |
- |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | strains lacking opuABCD accumulate more trehalose under stress conditions than wild-type strains. OpuABCD mutant strains are more resistant to high-salt, low-pH and -hydrogen peroxide, conditions that mimic aspects of innate immunity, in a trehalose-dependent manner. In addition, OpuABCD mutant strains require the trehalose production genes to outcompete wild-type strains in mice and macrophages | Salmonella enterica |
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Release 2023.1 (January 2023)
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