Crystallization (Comment) | Organism |
---|---|
BtuCD-F complex, and HI470/1 X-ray diffraction structure analysis using PDB-IDs 2NQ2, 1L7V and 2QI9, overview | Haemophilus influenzae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | periplasmic orientation | Haemophilus influenzae | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + vitamin B12/out | Haemophilus influenzae | - |
ADP + phosphate + vitamin B12/in | - |
? | |
additional information | Haemophilus influenzae | metal-chelate-type ABC transporter HI1470/1 is homologous with vitamin B12 importer BtuCD but exhibits a distinct inward-facing conformation in contrast to the outward-facing conformation of BtuCD. The outward-facing conformation of HI1470/1 is considered to be one of the intermediate states in the translocation cycle of BtuCD | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Haemophilus influenzae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + vitamin B12/out | - |
Haemophilus influenzae | ADP + phosphate + vitamin B12/in | - |
? | |
additional information | metal-chelate-type ABC transporter HI1470/1 is homologous with vitamin B12 importer BtuCD but exhibits a distinct inward-facing conformation in contrast to the outward-facing conformation of BtuCD. The outward-facing conformation of HI1470/1 is considered to be one of the intermediate states in the translocation cycle of BtuCD | Haemophilus influenzae | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | BtuCD structure analysis, overview | Haemophilus influenzae |
More | HI1470/1 shows intrinsic asymmetric conformational flexibility. The metal-chelate-type ABC transporter HI1470/1 is homologous with vitamin B12 importer BtuCD but exhibits a distinct inward-facing conformation in contrast to the outward-facing conformation of BtuCD. The outward-facing conformation of HI1470/1 is considered to be one of the intermediate states in the translocation cycle of BtuCD | Haemophilus influenzae |
Synonyms | Comment | Organism |
---|---|---|
BtuCD | - |
Haemophilus influenzae |
vitamin B12 importer | - |
Haemophilus influenzae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Haemophilus influenzae |