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Literature summary for 7.6.2.3 extracted from
- Application of human placental villous tissue explants to study ABC transporter mediated efflux of 2,4-dinitrophenyl-S-glutathione (2011), Curr. Pharm. Biotechnol., 12, 814-823 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| sodium orthovanadate | - |
Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q92887 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| chorionic villus | - |
Homo sapiens | - |
| placenta | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + 2,4-dinitrophenyl-S-glutathione[side 1] | - |
Homo sapiens | ADP + phosphate + 2,4-dinitrophenyl-S-glutathione[side 2] | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 180000, P-glycoprotein, SDS-PAGE | Homo sapiens |
| ? | x * 190000, MRP2, SDS-PAGE | Homo sapiens |
| ? | x * 70000, BCRP, SDS-PAGE | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| BCRP | - |
Homo sapiens |
| breast cancer resistance protein | - |
Homo sapiens |
| MRP2 | - |
Homo sapiens |
| multidrug resistance associated protein 2 | - |
Homo sapiens |
| P-glycoprotein | - |
Homo sapiens |
| P-gp | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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