Literature summary for 7.6.2.2 extracted from

Tachibana, T.; Kato, M.; Watanabe, T.; Mitsui, T.; Sugiyama, Y.
Method for predicting the risk of drug-drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein (2009), Xenobiotica, 39, 430-443.

Search for more literature for 7.6.2.2

Application

Application	Comment	Organism
medicine	development of a method for predicting the risk of drug-drug interactions involving inhibition of P-glycoprotein	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + digoxin/in	-	Homo sapiens	ADP + phosphate + digoxin/out	-	?
ATP + H2O + fexofenadine/in	-	Homo sapiens	ADP + phosphate + fexofenadine/out	-	?
ATP + H2O + talinolol/in	-	Homo sapiens	ADP + phosphate + talinolol/out	-	?

Synonyms

Synonyms	Comment	Organism
P-glycoprotein	-	Homo sapiens

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Release 2023.1 (January 2023)