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Literature summary for 7.6.2.10 extracted from

  • Tsigelny, I.F.; Greenberg, J.; Kouznetsova, V.; Nigam, S.K.
    Modeling of glycerol-3-phosphate transporter suggests a potential tilt mechanism involved in its function (2008), J. Bioinform. Comput. Biol., 6, 885-904.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.6.2.10

Crystallization (Commentary)

Crystallization (Comment) Organism
crystal structure analysis of GlpT for structure modelling Homo sapiens

Protein Variants

Protein Variants Comment Organism
G149E site-directed mutagenesis, structure analysis Homo sapiens
R28C site-directed mutagenesis, structure analysis Homo sapiens
R28C/W118R/G149E site-directed mutagenesis, structure analysis Homo sapiens
W118R site-directed mutagenesis, structure analysis Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane the enzyme contains 12-transmembrane alpha-helical topologies with two six-helix halves connected by a long loop Homo sapiens 16020
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Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information a major conformational switching mechanism accounts for ligand transport by MFS proteins Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
More interdomain interaction analysis and enzyme structure modelling, steered molecular dynamics simulation, overview Homo sapiens

Synonyms

Synonyms Comment Organism
GlpT
-
 Homo sapiens
glycerol-3-phosphate transporter
-
 Homo sapiens
More the enzyme belongs to the major facilitator MFS transporter superfamily Homo sapiens