Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endosome | - |
Homo sapiens | 5768 | - |
Golgi apparatus | - |
Homo sapiens | 5794 | - |
plasma membrane | - |
Homo sapiens | 5886 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + phosphatidylserine[side 1] | Homo sapiens | - |
ADP + phosphate + phosphatidylserine[side 2] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O75110 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + phosphatidylserine[side 1] | - |
Homo sapiens | ADP + phosphate + phosphatidylserine[side 2] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ATP9A | - |
Homo sapiens |
P4-ATPase | - |
Homo sapiens |
phospholipid flippase | - |
Homo sapiens |
type IV P-type ATPase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme depletion delays the recycling of transferrin from endosomes to the plasma membrane and causes accumulation of glucose transporter 1 in endosomes, probably by inhibiting their recycling | Homo sapiens |
metabolism | the enzyme is required for the recycling pathway from the endosomes to the plasma membrane | Homo sapiens |