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BRENDA support

Literature summary for 7.6.2.1 extracted from

  • Siggs, O.M.; Arnold, C.N.; Huber, C.; Pirie, E.; Xia, Y.; Lin, P.; Nemazee, D.; Beutler, B.
    The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow (2011), Nat. Immunol., 12, 434-440.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus Q9QZW0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fetus
-
Mus musculus
-
liver
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Mus musculus
-

Synonyms

Synonyms Comment Organism
aminophospholipid flippase
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Mus musculus
ATP11C
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Mus musculus
P4-type ATPase
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Mus musculus

General Information

General Information Comment Organism
physiological function the P4-type ATPase ATP11C is redundant during B cell development in the fetal liver, yet essential in the context of adult bone marrow, where it is required for optimal responses to interleukin-7 and sustained expression of Ebf1 Mus musculus