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Literature summary for 7.4.2.6 extracted from
- Functional role of oppA encoding an oligopeptide-binding protein from Lactobacillus salivarius Ren in bile tolerance (2015), J. Ind. Microbiol. Biotechnol., 42, 1167-1174.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Lactococcus lactis strain NZ9000 | Ligilactobacillus salivarius |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cell surface | - |
Ligilactobacillus salivarius | 9986 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 58000 | - |
x * 58000, mature enzyme, SDS-PAGE | Ligilactobacillus salivarius |
| 61700 | - |
x * 61700, calculated from amino acid sequence | Ligilactobacillus salivarius |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + olipopeptide/out | Ligilactobacillus salivarius | - |
ADP + phosphate + oligopeptide/in | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Ligilactobacillus salivarius | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + olipopeptide/out | - |
Ligilactobacillus salivarius | ADP + phosphate + oligopeptide/in | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 58000, mature enzyme, SDS-PAGE | Ligilactobacillus salivarius |
| ? | x * 61700, calculated from amino acid sequence | Ligilactobacillus salivarius |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| oligopeptide transporter substrate-binding protein | - |
Ligilactobacillus salivarius |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme confers specific resistance to taurine-conjugated bile salts. Enzyme overexpression confers 20fold higher tolerance to 0.5% oxgall in Lactobacillus salivarius as well as 1.8fold and 3.6fold higher survival when exposed to the sublethal concentration of sodium taurocholate and sodium taurodeoxycholate, respectively, while no significant change is observed when exposed to sodium glycocholate and sodium glycodeoxycholate. In addition, enzyme overexpression also leads to significantly increased resistance to heat (55°C) and salt (7.5% (w/v) NaCl) stresses | Ligilactobacillus salivarius |
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Release 2023.1 (January 2023)
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