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Literature summary for 7.4.2.2 extracted from

  • Sekito, T.; Fujiki, Y.; Ohsumi, Y.; Kakinuma, Y.
    Novel families of vacuolar amino acid transporters (2008), IUBMB Life, 60, 519-525.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
vacuolar membrane
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Saccharomyces cerevisiae 5774
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + nonpolar amino acid/out Saccharomyces cerevisiae vacuolar compartmentalization of amino acids: basic amino acids, e.g. tyrosine, leucine and isoleucine, accumulate preferentially into vacuoles but acidic amino acids are almost excluded from them, the enzyme acts as part of selective machineries to transport the amino acids operating at the vacuolar membrane ADP + phosphate + nonpolar amino acid/in
-
?
additional information Saccharomyces cerevisiae amino acid compartmentalization in vacuoles is dynamically linked with such a homeostatic function for the maintenance of the cytosolic amino acid concentration in yeast ?
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + nonpolar amino acid/out vacuolar compartmentalization of amino acids: basic amino acids, e.g. tyrosine, leucine and isoleucine, accumulate preferentially into vacuoles but acidic amino acids are almost excluded from them, the enzyme acts as part of selective machineries to transport the amino acids operating at the vacuolar membrane Saccharomyces cerevisiae ADP + phosphate + nonpolar amino acid/in
-
?
ATP + H2O + nonpolar amino acid/out Arg, Lys, His, Phe, Trp, Tyr, Gln, Asn, Ile and Leu are actively transported into vacuoles by several different transporters, overview. VBA family enzymes transport basic amino acids, such as arginine, histidine and lysine, into yeast vacuoles Saccharomyces cerevisiae ADP + phosphate + nonpolar amino acid/in
-
?
additional information amino acid compartmentalization in vacuoles is dynamically linked with such a homeostatic function for the maintenance of the cytosolic amino acid concentration in yeast Saccharomyces cerevisiae ?
-
?

Synonyms

Synonyms Comment Organism
More the vacuolar amino acid transporters belong to the AVT family or the VBA family of enzymes Saccharomyces cerevisiae
vacuolar amino acid transporter
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Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
ATP
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Saccharomyces cerevisiae