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Literature summary for 7.4.2.11 extracted from

  • Gal, J.; Szvetnik, A.; Schnell, R.; Kalman, M.
    The metD D-methionine transporter locus of Escherichia coli is an ABC transporter gene cluster (2002), J. Bacteriol., 184, 4930-4932 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.4.2.11

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli JM109 cells Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + D-methionine-[methionine-binding protein][side 1] Escherichia coli
-
 ADP + phosphate + D-methionine[side 2] + [methionine-binding protein][side 1]
-
 ?
ATP + H2O + L-methionine-[methionine-binding protein][side 1] Escherichia coli
-
 ADP + phosphate + L-methionine[side 2] + [methionine-binding protein][side 1]
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + alpha-methyl methionine-[methionine-binding protein][side 1]
-
 Escherichia coli ADP + phosphate + alpha-methyl methionine[side 2] + [methionine-binding protein][side 1]
-
 ?
ATP + H2O + D-methionine-[methionine-binding protein][side 1]
-
 Escherichia coli ADP + phosphate + D-methionine[side 2] + [methionine-binding protein][side 1]
-
 ?
ATP + H2O + L-methionine-[methionine-binding protein][side 1]
-
 Escherichia coli ADP + phosphate + L-methionine[side 2] + [methionine-binding protein][side 1]
-
 ?

Synonyms

Synonyms Comment Organism
D-methionine transporter
-
 Escherichia coli
metD locus name Escherichia coli
metNIQ
-
 Escherichia coli

Expression

Organism Comment Expression
Escherichia coli enzyme expression decreased about 3fold upon the addition of L-methionine to the medium and about 2fold when the metJ gene is present in multicopy. When both L-methionine is added and metJ is present in multicopy, the enzyme expression decreases about 12fold down