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Literature summary for 7.4.2.10 extracted from

  • Dygas, A.; Makowski, P.; Pikula, S.
    Is the glutathione conjugate of trans-4-hydroxy-2-nonenal transported by the multispecific organic anion transporting-ATPase of human erythrocytes? (1998), Acta Biochim. Pol., 45, 59-65 .
    View publication on PubMed
Search for more literature for 7.4.2.10

Inhibitors

Inhibitors Comment Organism Structure
glutathione-[trans-4-hydroxy-2-nonenal] competitive inhibition with respect to S-(2,4-dinitrophenyl)glutathione Homo sapiens
trans-4-hydroxy-2-nonenal non-competitive inhibition with respect to S-(2,4-dinitrophenyl)glutathione Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Homo sapiens 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ 2 mM used in assay conditions Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + glutathione-[trans-4-hydroxy-2-nonenal][side 1]
-
 Homo sapiens ADP + phosphate + glutathione[side 2] + [trans-4-hydroxy-2-nonenal][side 1]
-
 ?
ATP + H2O + S-(2,4-dinitrophenyl)glutathione[side1]
-
 Homo sapiens ADP + phosphate + glutathione[side 2] + 2,4-dinitrophenol[side 1]
-
 ?

Synonyms

Synonyms Comment Organism
MOAT3
-
 Homo sapiens
multispecific organic anion transporting-ATPase
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0002
-
 glutathione-[trans-4-hydroxy-2-nonenal] at pH 7.4 ad 37°C Homo sapiens
0.22
-
 trans-4-hydroxy-2-nonenal at pH 7.4 ad 37°C Homo sapiens