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Literature summary for 7.4.2.1 extracted from

  • Trip, H.; Evers, M.E.; Kiel, J.A.; Driessen, A.J.
    Uptake of the b-lactam precursor a-aminoadipic acid in Penicillium chrysogenum is mediated by the acidic and the general amino acid permease (2004), Appl. Environ. Microbiol., 70, 4775-4783.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.4.2.1

Cloned(Commentary)

Cloned (Comment) Organism
expression in Saccharomyces cerevisiae mutant M4276 Penicillium chrysogenum

Inhibitors

Inhibitors Comment Organism Structure
leucine inhibits alpha-aminoadipic acid transport via PcGap1 Penicillium chrysogenum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.23
-
 alpha-aminoadipic acid-[polar amino acid-binding protein][side 1]
-
 Penicillium chrysogenum

Organism

Organism UniProt Comment Textmining
Penicillium chrysogenum
-
-
-
Penicillium chrysogenum Wisconsin 54-1255
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + alpha-aminoadipic acid-[polar amino acid-binding protein][side 1]
-
 Penicillium chrysogenum ADP + phosphate + alpha-aminoadipic acid[side 2] + [polar amino acid-binding protein][side 1]
-
 ?
ATP + H2O + alpha-aminoadipic acid-[polar amino acid-binding protein][side 1]
-
 Penicillium chrysogenum Wisconsin 54-1255 ADP + phosphate + alpha-aminoadipic acid[side 2] + [polar amino acid-binding protein][side 1]
-
 ?
additional information contributes to the alpha-aminoadipic acid flux Penicillium chrysogenum ?
-
 ?
additional information contributes to the alpha-aminoadipic acid flux Penicillium chrysogenum Wisconsin 54-1255 ?
-
 ?

Synonyms

Synonyms Comment Organism
general amino acid permease
-
 Penicillium chrysogenum
PcGap1
-
 Penicillium chrysogenum