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Literature summary for 7.3.2.6 extracted from

  • Kazakov, A.E.; Rajeev, L.; Luning, E.G.; Zane, G.M.; Siddartha, K.; Rodionov, D.A.; Dubchak, I.; Arkin, A.P.; Wall, J.D.; Mukhopadhyay, A.; Novichkov, P.S.
    New family of tungstate-responsive transcriptional regulators in sulfate-reducing bacteria (2013), J. Bacteriol., 195, 4466-4475.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Desulfovibrio vulgaris Q72FN2 gene modB; harbors genes modABC, no tupBAC genes
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Desulfovibrio vulgaris Q72FN3 gene modC; harbors genes modABC, no tupBAC genes
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Desulfovibrio vulgaris Q72FN6 gene modA; harbors genes modABC, no tupBAC genes
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Desulfovibrio vulgaris Hildenborough Q72FN2 gene modB; harbors genes modABC, no tupBAC genes
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Desulfovibrio vulgaris Hildenborough Q72FN3 gene modC; harbors genes modABC, no tupBAC genes
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Desulfovibrio vulgaris Hildenborough Q72FN6 gene modA; harbors genes modABC, no tupBAC genes
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Expression

Organism Comment Expression
Desulfovibrio vulgaris activation of modA and modBC genes by TunR in Desulfovibrio vulgaris in vivo up

General Information

General Information Comment Organism
metabolism specific high-affinity ATP-binding cassette (ABC) transporting systems uptake molybdenum and tungsten in the form of soluble oxyanions, molybdate and tungstate. Among them are the bacterial TupABC transporting system, which is highly specific for tungstate and does not transport other anions, and the ModABC system, which can transport both molybdate and tungstate, regulation of the ModABC transport system. TunR proteins participate in protection of the cells from the inhibition by these oxyanions Desulfovibrio vulgaris
physiological function regulator family, tungstate-responsive regulator (TunR) controls the homeostasis of tungstate and molybdate in sulfate-reducing delta-proteobacteria, activation of modA and modBC genes by TunR in Desulfovibrio vulgaris in vivo by a ModE-like regulatory mechanism Desulfovibrio vulgaris