Literature summary for 7.2.4.5 extracted from

Haertel, U.; Buckel, W.
Sodium ion-dependent hydrogen production in Acidaminococcus fermentans (1996), Arch. Microbiol., 166, 350-356 .

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Organism

Organism	UniProt	Comment	Textmining
Acidaminococcus fermentans	Q06700 and Q9ZAA6 and Q9ZAA7 and Q9ZAA8	Q06700 i.e. subunit GcdA, Q9ZAA6 .e. subunit GcdB, Q9ZAA7 .e. subunit GcdC, Q9ZAA8 .e. subunit GcdD	-
Acidaminococcus fermentans DSM 20731	Q06700 and Q9ZAA6 and Q9ZAA7 and Q9ZAA8	Q06700 i.e. subunit GcdA, Q9ZAA6 .e. subunit GcdB, Q9ZAA7 .e. subunit GcdC, Q9ZAA8 .e. subunit GcdD	-

General Information

General Information	Comment	Organism
physiological function	Acidaminococcus fermentans is able to ferment glutamate to ammonia, CO2, acetate, butyrate, and H2. H2 formation is dependent on Na+ in washed cells. According to the model, electrons, generated by NADH oxidation inside of the cytoplasmic membrane, reduce protons outside of the cytoplasmic membrane. The entire process can be driven by decarboxylation of glutaconyl-CoA, which consumes the protons released by NADH oxidation inside the cell. Hydrogen production commences exactly at those Na+ concentrations at which the electrogenic H+/Na+-antiporter glutaconyl-CoA decarboxylase is converted into a Na+/Na+ exchanger	Acidaminococcus fermentans

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Release 2023.1 (January 2023)