Cloned (Comment) | Organism |
---|---|
expressed in Sf9 insect cells | Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
S258A | the mutation abrogates all cAMP-dependent protein kinase-mediated phosphorylations of the enzyme (with an 8fold decrease in the burst of initial phosphorylation) | Saccharomyces cerevisiae |
S258A/S971A | the mutations lead to an increase in its cAMP-dependent protein kinase-mediated global regulatory phosphorylation | Saccharomyces cerevisiae |
S258D | the phosphomimetic mutant exhibits extremely slow phosphorylation | Saccharomyces cerevisiae |
S971A | the mutation leads to a 100% increase in its cAMP-dependent protein kinase-mediated global regulatory phosphorylation | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
Golgi apparatus | - |
Saccharomyces cerevisiae | 5794 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
110000 | - |
x * 110000, SDS-PAGE | Saccharomyces cerevisiae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | P38995 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the enzyme undergoes auto-phosphorylation on Asp627 | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Cu2+/in | - |
Saccharomyces cerevisiae | ADP + phosphate + Cu2+/out | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 110000, SDS-PAGE | Saccharomyces cerevisiae |
Synonyms | Comment | Organism |
---|---|---|
Ccc2 | - |
Saccharomyces cerevisiae |
copper-transporting ATPase | - |
Saccharomyces cerevisiae |
Cu(I)-ATPase | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme pumps copper from the cytosol to the Golgi lumen | Saccharomyces cerevisiae |