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Literature summary for 7.2.2.9 extracted from

  • Ahmed, Z.; Deyama, Y.; Yoshimura, Y.; Suzuki, K.
    Cisplatin sensitivity of oral squamous carcinoma cells is regulated by Na+,K+-ATPase activity rather than copper-transporting P-type ATPases, ATP7A and ATP7B (2009), Cancer Chemother. Pharmacol., 63, 643-650.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Homo sapiens 16020
-
microsome
-
Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Cu2+/in Homo sapiens
-
ADP + phosphate + Cu2+/out
-
?
additional information Homo sapiens cisplatin sensitivity of oral squamous carcinoma cells is regulated by Na+,K+-ATPase activity rather than copper-transporting P-type ATPases ATP7A and ATP7B ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BHY cell
-
Homo sapiens
-
HSC-3 cell
-
Homo sapiens
-
oral squamous cell carcinoma cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Cu2+/in
-
Homo sapiens ADP + phosphate + Cu2+/out
-
?
additional information cisplatin sensitivity of oral squamous carcinoma cells is regulated by Na+,K+-ATPase activity rather than copper-transporting P-type ATPases ATP7A and ATP7B Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
ATP7A
-
Homo sapiens
ATP7B
-
Homo sapiens
copper-transporting P-type ATPase
-
Homo sapiens
Cu2+-ATPase
-
Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
assay at Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens