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Literature summary for 7.2.2.9 extracted from

  • Vanderwerf, S.M.; Cooper, M.J.; Stetsenko, I.V.; Lutsenko, S.
    Copper specifically regulates intracellular phosphorylation of the Wilson's disease protein, a human copper-transporting ATPase (2001), J. Biol. Chem., 276, 36289-36294.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of the wild type and truncated mutants in COS-7 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein two phosphorilation sites, phosphorilation is induced by copper Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
hepatoma cell Hep3B Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Cu2+/in
-
Homo sapiens ADP + phosphate + Cu2+/out
-
r

Synonyms

Synonyms Comment Organism
ATP7B
-
Homo sapiens
Wilson's disease protein
-
Homo sapiens
WNDP
-
Homo sapiens