Literature summary for 7.2.2.8 extracted from

Zhu, S.; Shanbhag, V.; Hodgkinson, V.L.; Petris, M.J.
Multiple di-leucines in the ATP7A copper transporter are required for retrograde trafficking to the trans-Golgi network (2016), Metallomics, 8, 993-1001 .

Search for more literature for 7.2.2.8

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli. The use of DNA synthesis to generate silent mutations across the majority of both mouse and human ATP7A open reading frames is sufficient to stabilize the genes in high-copy plasmids	Mus musculus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
Golgi apparatus	a second di-leucine motif in the carboxy tail of ATP7A (1459LL) is essential for steady-state localization in the trans-Golgi network by functioning in endosome-to-trans-Golgi network trafficking. Multiple di-leucine signals are required for recycling ATP7A from the plasma membrane to the trans-Golgi network	Mus musculus	5794	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q64430	-	-

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Release 2023.1 (January 2023)