Cloned (Comment) | Organism |
---|---|
for expression in Escherichia coli cells | Haemophilus influenzae |
Protein Variants | Comment | Organism |
---|---|---|
E149Q | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 95% | Haemophilus influenzae |
F162L | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 104% | Haemophilus influenzae |
G155A | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 76% | Haemophilus influenzae |
G155E | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 111% | Haemophilus influenzae |
G155V | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 88% | Haemophilus influenzae |
G418A | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 38% | Haemophilus influenzae |
I174F | effect of permease mutaion on transport is measured, remaining transport rate 27% | Haemophilus influenzae |
I174N | effect of permease mutaion on transport is measured, remaining transport rate 89% | Haemophilus influenzae |
I174N/S475I | effect of permease mutaion on transport is measured, remaining transport rate 9% | Haemophilus influenzae |
I383N | effect of permease mutaion on transport is measured, remaining transport rate 100% | Haemophilus influenzae |
I497V | effect of permease mutaion on transport is measured, remaining transport rate 100% | Haemophilus influenzae |
L154D | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 35% | Haemophilus influenzae |
L417D | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 5% | Haemophilus influenzae |
P168A | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 116% | Haemophilus influenzae |
S146Y | effect of permease mutaion on transport is measured, remaining transport rate 18% | Haemophilus influenzae |
S153A | effect of motif 1 and 2 mutations on transport is measured, remaining transport rate 112% | Haemophilus influenzae |
S475I | effect of permease mutaion on transport is measured, remaining transport rate 12% | Haemophilus influenzae |
V497I | effect of permease mutaion on transport is measured, remaining transport rate 23% | Haemophilus influenzae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
gallium | - |
Haemophilus influenzae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Fe3+/out | Haemophilus influenzae | shuttling of free Fe3+ through the periplasm | ADP + phosphate + Fe3+/in | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Haemophilus influenzae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Fe3+/out | shuttling of free Fe3+ through the periplasm | Haemophilus influenzae | ADP + phosphate + Fe3+/in | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Fe3+transporting ATPase | - |
Haemophilus influenzae |
hFbpABC transporter | - |
Haemophilus influenzae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
radio-labeled iron transport assay | Haemophilus influenzae |