Literature summary for 7.2.2.4 extracted from

Ogura, M.; Tsukahara, K.; Hayashi, K.; Tanaka, T.
The Bacillus subtilis NatK-NatR two-component system regulates expression of the natAB operon encoding an ABC transporter for sodium ion extrusion (2007), Microbiology, 153, 667-675 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + Na+[side 1]	Bacillus subtilis	-	ADP + phosphate + Na+[side 2]	-	?
ATP + H2O + Na+[side 1]	Bacillus subtilis 168	-	ADP + phosphate + Na+[side 2]	-	?

Organism

Organism	UniProt	Comment	Textmining
Bacillus subtilis	P46903	-	-
Bacillus subtilis	P46904	-	-
Bacillus subtilis 168	P46903	-	-
Bacillus subtilis 168	P46904	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-affinity column chromatography	Bacillus subtilis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Na+[side 1]	-	Bacillus subtilis	ADP + phosphate + Na+[side 2]	-	?
ATP + H2O + Na+[side 1]	-	Bacillus subtilis 168	ADP + phosphate + Na+[side 2]	-	?

Synonyms

Synonyms	Comment	Organism
NatA	-	Bacillus subtilis
natAB	operon name	Bacillus subtilis
natB	-	Bacillus subtilis

Expression

Organism	Comment	Expression
Bacillus subtilis	the NatK-NatR response regulator system positively regulates the expression of the enzyme	up

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Release 2023.1 (January 2023)