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Literature summary for 7.2.2.3 extracted from

  • Hu, Y.; Wang, Z.; Ge, N.; Huang, T.; Zhang, M.; Wang, H.
    Sodium pump alpha-2 subunit (ATP1A2) alleviates cardiomyocyte anoxia-reoxygenation injury via inhibition of endoplasmic reticulum stress-related apoptosis (2018), Can. J. Physiol. Pharmacol., 96, 515-520 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + K+[side 1] Rattus norvegicus
-
 ADP + phosphate + K+[side 2]
-
 ?
ATP + H2O + Na+[side 1] Rattus norvegicus
-
 ADP + phosphate + Na+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P06686
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
cardiomyocyte
-
 Rattus norvegicus
-
myocardium
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + K+[side 1]
-
 Rattus norvegicus ADP + phosphate + K+[side 2]
-
 ?
ATP + H2O + Na+[side 1]
-
 Rattus norvegicus ADP + phosphate + Na+[side 2]
-
 ?

Synonyms

Synonyms Comment Organism
ATP1A2 subunit Rattus norvegicus
Na+-K+-ATPase alpha-2 subunit
-
 Rattus norvegicus
sodium pump
-
 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus subunit ATP1A2 expression is downregulated upon anoxia-reoxygenation injury down

General Information

General Information Comment Organism
physiological function cardiomyocyte ATP1A2 is a target of anoxia-reoxygenation injury Rattus norvegicus