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Literature summary for 7.2.2.20 extracted from

  • Gunasekera, T.S.; Herre, A.H.; Crowder, M.W.
    Absence of ZnuABC-mediated zinc uptake affects virulence-associated phenotypes of uropathogenic Escherichia coli CFT073 under Zn(II)-depleted conditions (2009), FEMS Microbiol. Lett., 300, 36-41 .
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Zn2+-[zinc-binding protein][side1] Escherichia coli
-
 ADP + phosphate + Zn2+[side2] + [zinc-binding protein][side2]
-
 ?
ATP + H2O + Zn2+-[zinc-binding protein][side1] Escherichia coli CFT073
-
 ADP + phosphate + Zn2+[side2] + [zinc-binding protein][side2]
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli CFT073
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Zn2+-[zinc-binding protein][side1]
-
 Escherichia coli ADP + phosphate + Zn2+[side2] + [zinc-binding protein][side2]
-
 ?
ATP + H2O + Zn2+-[zinc-binding protein][side1]
-
 Escherichia coli CFT073 ADP + phosphate + Zn2+[side2] + [zinc-binding protein][side2]
-
 ?

Synonyms

Synonyms Comment Organism
znuABC
-
 Escherichia coli

General Information

General Information Comment Organism
malfunction the absence of enzyme-mediated zinc uptake affects virulence-associated phenotypes of Escherichia coli CFT073 under zinc-depleted conditions. The subunit znuB-deletion mutant is significantly deficient in the formation of biofilm under static conditions and also shows a substantially reduced migration front of swarm cells Escherichia coli
physiological function the enzyme contributes to the virulence of Escherichia coli CFT073 in the urinary tract Escherichia coli