Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ADP | activates NTPase activity of the enzyme | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Sus scrofa | 16020 | - |
microsome | - |
Sus scrofa | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | activates, required for ATPase activity | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + H+/in + K+/out | Sus scrofa | - |
ADP + phosphate + H+/out + K+/in | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partially by preparation of enzyme-enriched microsomal vesicles | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
stomach | mucosa | Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
NTP hydrolysis activities, overview | Sus scrofa |
0.626 | - |
ATP hydrolysis in presence of 10 mM K+ and 0.003 mM valinomycin | Sus scrofa |
0.641 | - |
ATP hydrolysis in presence of 10 mM K+, 0.1 mM ADP, and 0.003 mM valinomycin | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + H+/in + K+/out | - |
Sus scrofa | ADP + phosphate + H+/out + K+/in | - |
? | |
additional information | the enzyme also performs K+-dependent NTP hydrolysis, utilizing ATP, GTP, CTP, UTP, and ITP, and an NTP/ADP exchange reaction, overview | Sus scrofa | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
H,K-ATPase | - |
Sus scrofa |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.8 | - |
assay at | Sus scrofa |