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Literature summary for 7.2.2.19 extracted from

  • Codina, J.; Li, J.; DuBose, T.D., Jr.
    CD63 interacts with the carboxy terminus of the colonic H+-K+-ATPase to increase plasma membrane localization and 86Rb+ uptake (2005), Am. J. Physiol., 288, C1279-C1286.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
additional information CD63 functions as a negative regulator of the colonic H+-K+-ATPase, specifically interacts with carboxy terminus of the enzyme, supression of CD63 protein synthesis in HEK-293 cells increases Rb+ uptake by the HKalpha2/NKbeta1 complex Mus musculus
additional information CD63 functions as a negative regulator of the colonic H+-K+-ATPase, specifically interacts with carboxy terminus of the enzyme, supression of CD63 protein synthesis in HEK-293 cells increases Rb+ uptake by the HKalpha2/NKbeta1 complex Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
transfection of Saccharomyces cerevisiae AH109 with pGBKT7 containing an insert encoding the 84 carboxy-terminal acids of HKalpha2, cotransfection of HEK-293 cells with HKalpha2 plus NKbeta1 Mus musculus
transfection of Saccharomyces cerevisiae AH109 with pGBKT7 containing an insert encoding the 84 carboxy-terminal acids of HKalpha2, cotransfection of HEK-293 cells with HKalpha2 plus NKbeta1 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Mus musculus 16020
-
membrane
-
Rattus norvegicus 16020
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon
-
Mus musculus
-
colon
-
Rattus norvegicus
-

Synonyms

Synonyms Comment Organism
H+-K+-ATPase
-
Mus musculus
H+-K+-ATPase
-
Rattus norvegicus
HKalpha2
-
Mus musculus
HKalpha2
-
Rattus norvegicus