Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.2.2.19 extracted from

  • Planelles, G.; Anagnostopoulos, T.; Cheval, L.; Doucet, A.
    Biochemical and functional characterization of H+-K+-ATPase in distal amphibian nephron (1991), Am. J. Physiol., 260, F806-812.
    View publication on PubMed
Search for more literature for 7.2.2.19

Inhibitors

Inhibitors Comment Organism Structure
imidazopyridine
-
 Necturus maculosus
Omeprazole
-
 Necturus maculosus
SCH28080
-
 Necturus maculosus
vanadate
-
 Necturus maculosus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.3
-
 K+
-
 Necturus maculosus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + H+/in + K+/out Necturus maculosus involved in urinary acidification ADP + phosphate + H+/out + K+/in
-
 ?
ATP + H2O + H+/in + K+/out Pelophylax ridibundus involved in urinary acidification ADP + phosphate + H+/out + K+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Necturus maculosus
-
-
-
Pelophylax ridibundus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
nephron high activity in the late distal and collecting tubules, undetectable in the proximal convoluted tubule and early distal tubule Necturus maculosus
-
nephron high activity in the late distal and collecting tubules, undetectable in the proximal convoluted tubule and early distal tubule Pelophylax ridibundus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + H+/in + K+/out
-
 Necturus maculosus ADP + phosphate + H+/out + K+/in
-
 ?
ATP + H2O + H+/in + K+/out
-
 Pelophylax ridibundus ADP + phosphate + H+/out + K+/in
-
 ?
ATP + H2O + H+/in + K+/out involved in urinary acidification Necturus maculosus ADP + phosphate + H+/out + K+/in
-
 ?
ATP + H2O + H+/in + K+/out involved in urinary acidification Pelophylax ridibundus ADP + phosphate + H+/out + K+/in
-
 ?