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Literature summary for 7.2.2.14 extracted from

  • Choi, E.; Choi, S.; Nam, D.; Park, S.; Han, Y.; Lee, J.S.; Lee, E.J.
    Elongation factor P restricts Salmonellas growth by controlling translation of a Mg2+ transporter gene during infection (2017), Sci. Rep., 7, 42098 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.14

Protein Variants

Protein Variants Comment Organism
P555A the MgtB mutant is functional for transporting Mg2+ to support growth in low Mg2+ media and shows higher replication within macrophages compared to the wild type Salmonella enterica
P556A the MgtB mutant is functional for transporting Mg2+ to support growth in low Mg2+ media and shows higher replication within macrophages compared to the wild type Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Mg2+[side 1] Salmonella enterica
-
 ADP + phosphate + Mg2+[side 2]
-
 ?
ATP + H2O + Mg2+[side 1] Salmonella enterica 14028s
-
 ADP + phosphate + Mg2+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
 serovar typhimurium
-
Salmonella enterica 14028s
-
 serovar typhimurium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Mg2+[side 1]
-
 Salmonella enterica ADP + phosphate + Mg2+[side 2]
-
 ?
ATP + H2O + Mg2+[side 1]
-
 Salmonella enterica 14028s ADP + phosphate + Mg2+[side 2]
-
 ?

Synonyms

Synonyms Comment Organism
Mg2+ transporter
-
 Salmonella enterica
Mg2+-transporting P-type ATPase
-
 Salmonella enterica
MgtB
-
 Salmonella enterica

Expression

Organism Comment Expression
Salmonella enterica inactivation of elongation factor P derepresses transcription of the mgtCBR operon and decreases MgtB protein levels down