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Literature summary for 7.2.2.14 extracted from
- Effects of strictosamide on mouse brain and kidney Na+, K+-ATPase and Mg2+-ATPase activities (2009), J. Ethnopharmacol., 121, 117-122.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| strictosamide | the main glycoalkaloid of Sarcocephalus latifolius leaves and roots, isolated from an ethanolic extract, used as medicinal plant in folk medicine, inhibits the enzyme in vitro and in vivo in kidney, but not in brain, by 45% at 2 mg/ml | Mus musculus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + Mg2+/out | Mus musculus | - |
ADP + phosphate + Mg2+/in | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
Charles River male mice | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.0000001 | - |
enzyme activity in kidney tissue | Mus musculus |
| 0.00000013 | - |
enzyme activity in brain tissue | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + H2O + Mg2+/out | - |
Mus musculus | ADP + phosphate + Mg2+/in | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Mg2+-ATPase | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Mus musculus | |
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