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Literature summary for 7.2.2.14 extracted from

  • Liapi, C.; Zarros, A.; Galanopoulou, P.; Theocharis, S.; Skandali, N.; Al-Humadi, H.; Anifantaki, F.; Gkrouzman, E.; Mellios, Z.; Tsakiris, S.
    Effects of short-term exposure to manganese on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na,K)-ATPase and Mg-ATPase: modulation by L-cysteine (2008), Basic Clin. Pharmacol. Toxicol., 103, 171-175.
    View publication on PubMed
Search for more literature for 7.2.2.14

Inhibitors

Inhibitors Comment Organism Structure
Mn2+ short term exposure to Mn2+, at 50 mg/kg body weight, inhibits the enzyme by 9%, possibly due to Mg2+ replacement. The effect is increased by addition of cysteine Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Mg2+/out Rattus norvegicus
-
 ADP + phosphate + Mg2+/in
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.119
-
 brain Mg2+-ATPase activity Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Mg2+/out
-
 Rattus norvegicus ADP + phosphate + Mg2+/in
-
 ?

Synonyms

Synonyms Comment Organism
Mg2+-ATPase
-
 Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Rattus norvegicus