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Literature summary for 7.2.2.13 extracted from

  • Liang, G.; Chung, T.; Guo, J.; Zhang, R.; Xü, W.; Tzen, J.; Jiang, R.
    Novel cinobufagin oxime ether derivatives as potential Na+/K+-ATPase inhibitors Synthesis, biological screening and molecular docking (2017), Chem. Res. Chin. Univ., 33, 378-383 .
No PubMed abstract available
Search for more literature for 7.2.2.13

Inhibitors

Inhibitors Comment Organism Structure
(3E,5beta,15beta,16beta)-16-(acetyloxy)-3-(hydroxyimino)-8-methyl-14,15-epoxybufa-20,22-dienolide
-
 Sus scrofa
(3E,5beta,15beta,16beta)-16-(acetyloxy)-3-(methoxyimino)-8-methyl-14,15-epoxybufa-20,22-dienolide
-
 Sus scrofa
(3E,5beta,15beta,16beta)-16-(acetyloxy)-3-[(2-aminoethoxy)imino]-8-methyl-14,15-epoxybufa-20,22-dienolide most potent inhibitor Sus scrofa
cinobufagin
-
 Sus scrofa
istaroxime
-
 Sus scrofa
Ouabain
-
 Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Sus scrofa 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Na+[side 1] + K+[side 2] Sus scrofa
-
 ADP + phosphate + Na+[side 2] + K+[side 1]
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+[side 1] + K+[side 2]
-
 Sus scrofa ADP + phosphate + Na+[side 2] + K+[side 1]
-
 ?

Synonyms

Synonyms Comment Organism
Na+/K+-ATPase
-
 Sus scrofa
NKA
-
 Sus scrofa
sodium pump
-
 Sus scrofa