Literature summary for 7.2.2.13 extracted from

Yang, P.; Cartwright, C.; Efuet, E.; Hamilton, S.R.; Wistuba, I.I.; Menter, D.; Addington, C.; Shureiqi, I.; Newman, R.A.
Cellular location and expression of Na+, K+ -ATPase alpha subunits affect the anti-proliferative activity of oleandrin (2014), Mol. Carcinog., 53, 253-263.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasmic membrane	the enzyme's alpha3 isoform is predominantly located near the cytoplasmic membrane in normal human colon and lung epithelia	Homo sapiens	-	-
nucleus	the enzyme's alpha3 isoform is predominantly located near the nucleus in cancerous human colon and lung epithelia	Homo sapiens	5634	-

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + H2O + Na+/in + K+/out	Homo sapiens	-	ADP + phosphate + Na+/out + K+/in	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Caco-2 cell	-	Homo sapiens	-
colon	-	Homo sapiens	-
lung epithelium	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + H2O + Na+/in + K+/out	-	Homo sapiens	ADP + phosphate + Na+/out + K+/in	-	?

Synonyms

Synonyms	Comment	Organism
Na+, K+ -ATPase	-	Homo sapiens

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Release 2023.1 (January 2023)