Literature summary for 7.2.2.13 extracted from

Feng, S.; Chen, W.; Cao, D.; Bian, J.; Gong, F.Y.; Cheng, W.; Cheng, S.; Xu, Q.; Hua, Z.C.; Yin, W.
Involvement of Na+, K+-ATPase and its inhibitors in HuR-mediated cytokine mRNA stabilization in lung epithelial cells (2011), Cell. Mol. Life Sci., 68, 109-124.

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Protein Variants

Protein Variants	Comment	Organism
additional information	reduction of Na+, K+-ATPase alpha1 subunit expression by siRNA transfection	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
foliandrin	-	Homo sapiens
oleandrin	-	Homo sapiens
Ouabain	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
plasma membrane	-	Homo sapiens	5886	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
A-549 cell	type II lung adenocarcinoma epithelial cells	Homo sapiens	-
lung epithelial cell	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
Na+, K+-ATPase	-	Homo sapiens

General Information

General Information	Comment	Organism
additional information	Na+, K+-ATPase inhibition by cardiotonic steroids increases COX-2 expression in A-549 cells, overview	Homo sapiens
physiological function	Na+, K+-ATPase plays an important role in pulmonary inflammation	Homo sapiens

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Release 2023.1 (January 2023)