Literature summary for 7.2.2.13 extracted from

Lima, F.D.; Oliveira, M.S.; Furian, A.F.; Souza, M.A.; Rambo, L.M.; Ribeiro, L.R.; Silva, L.F.; Retamoso, L.T.; Hoffmann, M.S.; Magni, D.V.; Pereira, L.; Fighera, M.R.; Mello, C.F.; Royes, L.F.
Adaptation to oxidative challenge induced by chronic physical exercise prevents Na+,K+-ATPase activity inhibition after traumatic brain injury (2009), Brain Res., 1279, 147-155.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	physical training is effective against Na+,K+-ATPase enzyme activity inhibition, while fluid percussion injury induces a decrease in Na+,K+-ATPase activity in the ipsilateral cerebral cortex of sedentary animals	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Rattus norvegicus	16020	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	cerebral, ipsilateral cortex	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
Na+,K+-ATPase	-	Rattus norvegicus

General Information

General Information	Comment	Organism
additional information	Na+,K+-ATPase alpha1 subunit is one of the targets for reactive oxygen species and is directly involved in oxidative stress. alpha1 Subunit level decrease after fluid percussion injury inducing traumatic brain injury in rats, overview. Physical training is effective against Na+,K+-ATPase enzyme activity inhibition, while fluid percussion injury induces a decrease in Na+,K+-ATPase activity in the ipsilateral cerebral cortex of sedentary animals	Rattus norvegicus

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Release 2023.1 (January 2023)