Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | increase in extracellular pH potentiates Na+-K+ pump activity | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | decrease in extracellular pH inhibits Na+-K+ pump activity | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphate + Na+/out | Rattus norvegicus | each cycle extrudes 3 Na+ from the cell and moves 2 K+ into the cell with utilization of 1 ATP | ATP + H2O + Na+/in | - |
? | |
ATP + H2O + K+/in | Rattus norvegicus | - |
ADP + phosphate + K+/out | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Sprague-Dawley rat | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
superior mesenteric artery | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphate + Na+/out | - |
Rattus norvegicus | ATP + H2O + Na+/in | - |
? | |
ADP + phosphate + Na+/out | each cycle extrudes 3 Na+ from the cell and moves 2 K+ into the cell with utilization of 1 ATP | Rattus norvegicus | ATP + H2O + Na+/in | - |
? | |
ATP + H2O + K+/in | - |
Rattus norvegicus | ADP + phosphate + K+/out | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Na+-K+ pump | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay conditions | Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.4 | 7.8 | variation of extracelluar pH for measurements of Na+-K+ pump activity | Rattus norvegicus |