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Literature summary for 7.2.2.13 extracted from

  • Kim Moon, Y.; Liang Guo, H.; Kim Ji, A.; Park Seong, H.; Hah Jong, S.; Suh Suk, H.
    Contribution of Na+-K+ pump and KIR currents to extracellular pH-dependent changes of contractility in rat superior mesenteric artery (2005), Am. J. Physiol., 289, H792-800.
    View publication on PubMed
Search for more literature for 7.2.2.13

Activating Compound

Activating Compound Comment Organism Structure
additional information increase in extracellular pH potentiates Na+-K+ pump activity Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
additional information decrease in extracellular pH inhibits Na+-K+ pump activity Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + Na+/out Rattus norvegicus each cycle extrudes 3 Na+ from the cell and moves 2 K+ into the cell with utilization of 1 ATP ATP + H2O + Na+/in
-
 ?
ATP + H2O + K+/in Rattus norvegicus
-
 ADP + phosphate + K+/out
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 Sprague-Dawley rat
-

Source Tissue

Source Tissue Comment Organism Textmining
superior mesenteric artery
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + Na+/out
-
 Rattus norvegicus ATP + H2O + Na+/in
-
 ?
ADP + phosphate + Na+/out each cycle extrudes 3 Na+ from the cell and moves 2 K+ into the cell with utilization of 1 ATP Rattus norvegicus ATP + H2O + Na+/in
-
 ?
ATP + H2O + K+/in
-
 Rattus norvegicus ADP + phosphate + K+/out
-
 ?

Synonyms

Synonyms Comment Organism
Na+-K+ pump
-
 Rattus norvegicus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay conditions Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
6.4 7.8 variation of extracelluar pH for measurements of Na+-K+ pump activity Rattus norvegicus