Cloned (Comment) | Organism |
---|---|
expression in Xenopus oocytes | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
oubain | K+ completely abolishes oubain binding to alpha1-beta1 isoenzymes. Residual oubain binding is still observed at high K+ concentrations for alpha2-beta1 and alpha3-beta1 complexes | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | completely abolishes oubain binding to alpha1-beta1 isoenzymes. Residual oubain binding is still observed at high K+ concentrations for alpha2-beta1 and alpha3-beta1 complexes | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Na+/in + K+/out | Homo sapiens | enzyme plays a crucial role in cellular ion homeostasis | ADP + phosphate + Na+/out + K+/in | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
9 different isoenzymes | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
oocyte | expression of different isoenzymes in Xenopus oocytes | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Na+/in + K+/out | - |
Homo sapiens | ADP + phosphate + Na+/out + K+/in | - |
? | |
ATP + H2O + Na+/in + K+/out | enzyme plays a crucial role in cellular ion homeostasis | Homo sapiens | ADP + phosphate + Na+/out + K+/in | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Homo sapiens |