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Literature summary for 7.2.2.13 extracted from

  • Shimura, M.; Tamai, M.; Akaike, N.
    Characterization of the electrogenic Na+-K+ pump in horizontal cells isolated from the carp retina (1998), Neuroscience, 86, 233-240.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
oubain
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Cyprinus carpio

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
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Cyprinus carpio 16020
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plasma membrane
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Cyprinus carpio 5886
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Organism

Organism UniProt Comment Textmining
Cyprinus carpio
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
retina existence of at least two isoforms of the pump in the horizontal cells Cyprinus carpio
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Na+/in + K+/out a continous Na+ influx exists across the plasma membrane in the presence of external Na+. When Na+ is removed from both external and internal solutions, a transient outward pump current is observed by adding K+ to the external solution, thus indicating that the transient pump current is activated by the residual intracellular Na+ Cyprinus carpio ADP + phosphate + Na+/out + K+/in
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