Protein Variants | Comment | Organism |
---|---|---|
D149A | the mutant shows about 135% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
D181A | the mutant shows wild type Zn2+-transporting activity | Arabidopsis thaliana |
D313A | the mutant shows about 130% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
D688A | the mutant shows about 20% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
E169A | the mutant shows about 25% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
F177A | the mutant shows about 95% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
F177L | the mutant shows about 40% of wild type Zn2+-transporting activity and reduced Cd2+-transporting activity (about 20%) compared to the wild type enzyme | Arabidopsis thaliana |
G360A | the mutant shows about 75% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
K138A | the mutant shows about 110% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
K667A | the mutant shows about 30% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
N151A | the mutant shows about 70% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
P366L | the mutant shows about 15% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
V154A | the mutant shows about 60% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
V154S | the mutant shows about 60% of wild type Zn2+-transporting activity | Arabidopsis thaliana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Cd2+[side 1] | Arabidopsis thaliana | - |
ADP + phosphate + Cd2+[side 2] | - |
? | |
ATP + H2O + Zn2+[side 1] | Arabidopsis thaliana | - |
ADP + phosphate + Zn2+[side 2] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Cd2+[side 1] | - |
Arabidopsis thaliana | ADP + phosphate + Cd2+[side 2] | - |
? | |
ATP + H2O + Zn2+[side 1] | - |
Arabidopsis thaliana | ADP + phosphate + Zn2+[side 2] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HMA4 | - |
Arabidopsis thaliana |
P1B ATPase heavy metal ATPase 4 | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is responsible for zinc and cadmium translocation from roots to shoots in Arabidopsis thaliana | Arabidopsis thaliana |