Literature summary for 7.2.2.12 extracted from

Barabasz, A.; Wilkowska, A.; Ruszczynska, A.; Bulska, E.; Hanikenne, M.; Czarny, M.; Kraemer, U.; Antosiewicz, D.M.
Metal response of transgenic tomato plants expressing P1B-ATPase (2012), Physiol. Plant., 145, 315-331.

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Organism

Organism	UniProt	Comment	Textmining
Arabidopsis halleri	Q2I7E8	-	-

Synonyms

Synonyms	Comment	Organism
HMA4	-	Arabidopsis halleri
P1B-ATPase	-	Arabidopsis halleri

General Information

General Information	Comment	Organism
physiological function	the protein is involved in xylem loading of zinc. Expression of P1B-ATPase HMA4 facilitates root-to-shoot zinc translocation and induces zinc uptake in a Zn2+ supply-dependent manner. Enzyme expression increases zinc excess, triggers iron deficiency in leaves and transcriptional activation of Fe-uptake systems in roots. Moreover, enzyme expression causes zinc overload of the apoplast, which may contribute to enhanced zinc sensitivity of transgenic tomato plants	Arabidopsis halleri

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Release 2023.1 (January 2023)