Activating Compound | Comment | Organism | Structure |
---|---|---|---|
1,2-dichlorobenzene | concentrations of 0.05-0.2 mM of 1,2-dichlorobenzene stimulate the hydrolytic activity of the enzyme in a medium-containing Ca2+-ionophore | Oryctolagus cuniculus | |
potassium oxalate | Ca2+ uptake is supported by potassium oxalate | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,2-dichlorobenzene | at concentrations of 0.25-0.75 mM, 1,2-dichlorobenzene inhibits the ATP hydrolysis to about 80%. Starting at 0.05 mM, 1,2-dichlorobenzene is able to uncouple the ratio of hydrolysis/Ca2+transporte | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
sarcoplasmic reticulum | - |
Oryctolagus cuniculus | 16529 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | dependent on | Oryctolagus cuniculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Ca2+[side 1] | Oryctolagus cuniculus | - |
ADP + phosphate + Ca2+[side 2] | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | - |
Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Ca2+[side 1] | - |
Oryctolagus cuniculus | ADP + phosphate + Ca2+[side 2] | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 110000, SDS-PAGE | Oryctolagus cuniculus |
Synonyms | Comment | Organism |
---|---|---|
Ca2+-ATPase | - |
Oryctolagus cuniculus |
SERCA | - |
Oryctolagus cuniculus |