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Literature summary for 7.2.2.10 extracted from

  • Sahoo, S.K.; Shaikh, S.A.; Sopariwala, D.H.; Bal, N.C.; Bruhn, D.S.; Kopec, W.; Khandelia, H.; Periasamy, M.
    The N terminus of sarcolipin plays an important role in uncoupling sarco-endoplasmic reticulum Ca2+-ATPase (SERCA) ATP hydrolysis from Ca2+ Transport (2015), J. Biol. Chem., 290, 14057-14067.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.2.2.10

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK cells Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Mus musculus 5783
-
sarcoplasmic reticulum
-
 Mus musculus 16529
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Ca2+[side 1] Mus musculus
-
 ADP + phosphate + Ca2+[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+[side 1]
-
 Mus musculus ADP + phosphate + Ca2+[side 2]
-
 ?

Synonyms

Synonyms Comment Organism
sarco-endoplasmic reticulum Ca2+-ATPase
-
 Mus musculus
sarcoendoplasmic reticulum Ca2+-ATPase
-
 Mus musculus
SERCA
-
 Mus musculus

General Information

General Information Comment Organism
physiological function the enzyme is responsible for intracellular Ca2+ homeostasis. Enzyme uncoupling of Ca2+ transport from ATP hydrolysis by sarcolipin increases heat production implicating sarcolipin-enzyme interaction in muscle thermogenesis Mus musculus