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Literature summary for 7.2.2.10 extracted from

  • Ferreira-Gomes, M.S.; Gonzalez-Lebrero, R.M.; de la Fuente, M.C.; Strehler, E.E.; Rossi, R.C.; Rossi, J.P.
    Calcium occlusion in plasma membrane Ca2+-ATPase (2011), J. Biol. Chem., 286, 32018-32025.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf9 cells Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
La3+ prevents the Mg2+-dependent transition E1P->E2P, acting noncompetitively with respect to Ca2+ and ATP Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Homo sapiens
-
-
plasma membrane
-
Homo sapiens 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ required, one calcium ion becomes occluded in the E1P-phosphorylated intermediate of the enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+/out
-
Homo sapiens ADP + phosphate + Ca2+/in
-
?

Synonyms

Synonyms Comment Organism
plasma membrane Ca2+ ATPase
-
Homo sapiens
PMCA
-
Homo sapiens