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Literature summary for 7.2.2.10 extracted from

  • Mackiewicz, U.; Maczewski, M.; Konior, A.; Tellez, J.O.; Nowis, D.; Dobrzynski, H.; Boyett, M.R.; Lewartowski, B.
    Sarcolemmal Ca2+-ATPase ability to transport Ca2+ gradually diminishes after myocardial infarction in the rat (2009), Cardiovasc. Res., 81, 546-554.
    View publication on PubMed
Search for more literature for 7.2.2.10

Inhibitors

Inhibitors Comment Organism Structure
carboxyeosin blocker of PMCA Rattus norvegicus
additional information the Ca2+ transporting function of SERCA2a is decreased by about 18% 1 week, 1 month, and 3 months after myocardial infarction, while PMCA1, 2, and 4 mRNAs are unchanged in the ventricular muscle 3 months after myocardial infarction Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
plasmalemma
-
 Rattus norvegicus
-
-
sarcolemma
-
 Rattus norvegicus 42383
-
sarcoplasmic reticulum
-
 Rattus norvegicus 16529
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ dependent on Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
myocyte
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+/cis
-
 Rattus norvegicus ADP + phosphate + Ca2+/trans
-
 ?

Synonyms

Synonyms Comment Organism
plasmalemmal Ca2+-ATPase
-
 Rattus norvegicus
PMCA1 isoform Rattus norvegicus
PMCA2 isoform Rattus norvegicus
PMCA4 isoform Rattus norvegicus
sarcolemmal Ca2+-ATPase
-
 Rattus norvegicus
sarcoplasmic reticulum Ca2+-ATPase
-
 Rattus norvegicus
SERCA
-
 Rattus norvegicus
SERCA2a isoform Rattus norvegicus