Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | Mg2+ at high concentration (10 mM) and high pH inhibits the ATPase by binding to low affinity sites made available by the high pH in the medium | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
sarcoplasmic reticulum | - |
Oryctolagus cuniculus | 16529 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | SERCA binds two Ca2+ per mole | Oryctolagus cuniculus | |
Mg2+ | 1 mM Mg2+ (a concentration equivalent to that of ATP) is an absolute requirement for ATPase activity | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + Ca2+/cis | - |
Oryctolagus cuniculus | ADP + phosphate + Ca2+/trans | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ca2+ ATPase of sarcoplasmic reticulum | - |
Oryctolagus cuniculus |
Ca2+ transport ATPase of sarco-endoplasmic reticulum | - |
Oryctolagus cuniculus |
SERCA | - |
Oryctolagus cuniculus |