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Literature summary for 7.2.2.10 extracted from

  • Cho, J.H.; Ko, K.M.; Singaravelu, G.; Ahnn, J.
    Caenorhabditis elegans PMR1, a P-type calcium ATPase, is important for calcium/manganese homeostasis and oxidative stress response (2005), FEBS Lett., 579, 778-782.
    View publication on PubMed
Search for more literature for 7.2.2.10

Cloned(Commentary)

Cloned (Comment) Organism
gene pmr1, expression pattern, overexpression of truncated pmr1 in transgenic worms Caenorhabditis elegans

Protein Variants

Protein Variants Comment Organism
additional information construction of a pmr1 knockout mutant, which shows high sensitivity to Mn2+ and EGTA, but also resistance to oxidative stress and suppression of highly reactive oxygen species sensitivity od smf3 RNA-mediated interference and daf16 worms, overview Caenorhabditis elegans

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
-
 Caenorhabditis elegans 5794
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+
-
 Caenorhabditis elegans
Mg2+
-
 Caenorhabditis elegans
Mn2+
-
 Caenorhabditis elegans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + Ca2+/cis Caenorhabditis elegans Ca2+-dependent ATPase and ATP-dependent Ca2+ transport activities ADP + phosphate + Ca2+/trans
-
 ?
ATP + H2O + Mn2+/cis Caenorhabditis elegans Mn2+-dependent ATPase and ATP-dependent Mn2+ transport activities ADP + phosphate + Mn2+/trans
-
 ?
additional information Caenorhabditis elegans the P-type calcium ATPase is important for calcium/manganese homeostasis and oxidative stress response ?
-
 ?

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
-
 strains N2, daf-16(m26), and daf-2(e1370)III, gene pmr1
-

Source Tissue

Source Tissue Comment Organism Textmining
hypodermal seam cell
-
 Caenorhabditis elegans
-
intestine
-
 Caenorhabditis elegans
-
additional information enzyme expression pattern, overview Caenorhabditis elegans
-
spermatheca
-
 Caenorhabditis elegans
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + Ca2+/cis Ca2+-dependent ATPase and ATP-dependent Ca2+ transport activities Caenorhabditis elegans ADP + phosphate + Ca2+/trans
-
 ?
ATP + H2O + Mn2+/cis Mn2+-dependent ATPase and ATP-dependent Mn2+ transport activities Caenorhabditis elegans ADP + phosphate + Mn2+/trans
-
 ?
additional information the P-type calcium ATPase is important for calcium/manganese homeostasis and oxidative stress response Caenorhabditis elegans ?
-
 ?

Synonyms

Synonyms Comment Organism
Ca2+/Mn2+ ATPase pump
-
 Caenorhabditis elegans
CePMR-1
-
 Caenorhabditis elegans
P-type calcium ATPase
-
 Caenorhabditis elegans
PMR1
-
 Caenorhabditis elegans