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Literature summary for 7.2.1.1 extracted from

  • Hayashi, M.; Nakayama, Y.; Yasui, M.; Maeda, M.; Furuishi, K.; Unemoto, T.
    FMN is covalently attached to a threonine residue in the NqrB and NqrC subunits of Na+-translocating NADH-quinone reductase from Vibrio alginolyticus (2001), FEBS Lett., 488, 5-8.
    View publication on PubMed
Search for more literature for 7.2.1.1

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Vibrio alginolyticus 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Na+ the reaction catalyzed by subunits NqrA to NqrE to produce ubiquinol specifically requires Na+ for activity. The reaction catalyzed by subunit NqrF which reduces ubiquinone by a one-electron transfer pathway to produce ubisemiquinone radical does not require Na+ for activity Vibrio alginolyticus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADH + H+ + ubiquinone + n Na+/in Vibrio alginolyticus
-
 NAD+ + ubiquinol + n Na+/out
-
 ?

Organism

Organism UniProt Comment Textmining
Vibrio alginolyticus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + H+ + ubiquinone + n Na+/in
-
 Vibrio alginolyticus NAD+ + ubiquinol + n Na+/out
-
 ?

Subunits

Subunits Comment Organism
heterohexamer
-
 Vibrio alginolyticus

Synonyms

Synonyms Comment Organism
Na+-translocating NADH-quinone oxidoreductase
-
 Vibrio alginolyticus
NQR
-
 Vibrio alginolyticus

Cofactor

Cofactor Comment Organism Structure
FAD subunit NqrF contains non-covalently bound FAD Vibrio alginolyticus
FMN part of NqrB and NqrC subunits Vibrio alginolyticus
NADH
-
 Vibrio alginolyticus
riboflavin
-
 Vibrio alginolyticus
[2Fe-2S]-center
-
 Vibrio alginolyticus