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Literature summary for 7.1.3.2 extracted from

  • Luoto, H.; Belogurov, G.; Baykov, A.; Lahti, R.; Malinen, A.
    Na+-translocating membrane pyrophosphatases are widespread in the microbial world and evolutionarily precede H+-translocating pyrophosphatases (2011), J. Biol. Chem., 286, 21633-21642 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.1.3.2

Activating Compound

Activating Compound Comment Organism Structure
K+ about 1.5fold stimulation at 50 mM Desulfuromonas acetoxidans
K+ about 3fold stimulation at 50 mM Clostridium tetani
K+ about 4fold stimulation at 50 mM Chlorobium limicola
K+ about 4fold stimulation at 50 mM Anaerostipes caccae

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Chlorobium limicola
expression in Escherichia coli Clostridium tetani
expression in Escherichia coli Desulfuromonas acetoxidans
expression in Escherichia coli Anaerostipes caccae

Organism

Organism UniProt Comment Textmining
Anaerostipes caccae
-
-
-
Chlorobium limicola
-
-
-
Clostridium tetani
-
-
-
Desulfuromonas acetoxidans
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
diphosphate + H2O + Na+[side 1]
-
 Chlorobium limicola 2 phosphate + Na+[side 2]
-
 ?
diphosphate + H2O + Na+[side 1]
-
 Clostridium tetani 2 phosphate + Na+[side 2]
-
 ?
diphosphate + H2O + Na+[side 1]
-
 Desulfuromonas acetoxidans 2 phosphate + Na+[side 2]
-
 ?
diphosphate + H2O + Na+[side 1]
-
 Anaerostipes caccae 2 phosphate + Na+[side 2]
-
 ?

General Information

General Information Comment Organism
physiological function enzyme belongs to a monophyletic clade comprising Na+-transporting PPases within the K+-dependent subfamily. A specific Glu residue located in the cytoplasm-membrane interface of transmembrane helix 6 appears to be central in the transport mechanism Chlorobium limicola
physiological function enzyme belongs to a monophyletic clade comprising Na+-transporting PPases within the K+-dependent subfamily. A specific Glu residue located in the cytoplasm-membrane interface of transmembrane helix 6 appears to be central in the transport mechanism Clostridium tetani
physiological function enzyme belongs to a monophyletic clade comprising Na+-transporting PPases within the K+-dependent subfamily. A specific Glu residue located in the cytoplasm-membrane interface of transmembrane helix 6 appears to be central in the transport mechanism Desulfuromonas acetoxidans
physiological function enzyme belongs to a monophyletic clade comprising Na+-transporting PPases within the K+-dependent subfamily. A specific Glu residue located in the cytoplasm-membrane interface of transmembrane helix 6 appears to be central in the transport mechanism Anaerostipes caccae