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Literature summary for 7.1.2.2 extracted from

  • Wang, Y.; Hou, Q.; Xiao, G.; Yang, S.; Di, C.; Si, J.; Zhou, R.; Ye, Y.; Zhang, Y.; Zhang, H.
    Selective ATP hydrolysis inhibition in F1Fo ATP synthase enhances radiosensitivity in non-small-cell lung cancer cells (A549) (2017), Oncotarget, 8, 53602-53612 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.1.2.2

Inhibitors

Inhibitors Comment Organism Structure
BTB06584
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + 4 H+[side 1] Homo sapiens
-
 ADP + phosphate + 4 H+[side 2]
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-
non-small cell lung cancer cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + 4 H+[side 1]
-
 Homo sapiens ADP + phosphate + 4 H+[side 2]
-
 r

Synonyms

Synonyms Comment Organism
ATP5alpha1 subunit Homo sapiens
F1FO-ATP synthase
-
 Homo sapiens
F1FO-ATPase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens X-ray radiation enhances gene expression in mRNA and protein level of subunit ATP5alpha1 up

General Information

General Information Comment Organism
physiological function the robust ATP-hydrolyzing activity occurs in ischemia for maintaining the transmembrane proton motive force of mitochondria inner membrane Homo sapiens