Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N,N'-dicyclohexylcarbodiimide | a nonspecific FOF1-ATPase inhibitor, inhibits ATPase activity and also other membrane mechanisms involved in H+ translocation, in a pH-dependent manner in hya mutants, overview | Escherichia coli |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Escherichia coli | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no stimulation of ATPase activity by K+ | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + H+/in | Escherichia coli | - |
ADP + phosphate + H+/out | - |
r | |
ATP + H2O + H+/in | Escherichia coli BW25113 | - |
ADP + phosphate + H+/out | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Escherichia coli BW25113 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + H2O + H+/in | - |
Escherichia coli | ADP + phosphate + H+/out | - |
r | |
ATP + H2O + H+/in | - |
Escherichia coli BW25113 | ADP + phosphate + H+/out | - |
r |
Synonyms | Comment | Organism |
---|---|---|
FoF1-ATPase | - |
Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Escherichia coli |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 7.5 | at pH 7.5 H+ efflux is stimulated in fhlA mutant, with defective transcriptional activator of Hyd-3 or Hyd-4, and lowered in hyaB or hybC mutants, with defective Hyd-1 or Hyd-2. At pH 5.5 H+ efflux in wild-type cells is lowered compared with that at pH 7.5, but is increased in fhlA mutant and absent in hyaB/hybC mutant, overview | Escherichia coli |