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Literature summary for 7.1.2.2 extracted from

  • Blbulyan, S.; Avagyan, A.; Poladyan, A.; Trchounian, A.
    Role of Escherichia coli different hydrogenases in H+ efflux and the FOF1-ATPase activity during glycerol fermentation at different pH (2010), Biosci. Rep., 31, 179-184.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N,N'-dicyclohexylcarbodiimide a nonspecific FOF1-ATPase inhibitor, inhibits ATPase activity and also other membrane mechanisms involved in H+ translocation, in a pH-dependent manner in hya mutants, overview Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Escherichia coli 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no stimulation of ATPase activity by K+ Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + H+/in Escherichia coli
-
ADP + phosphate + H+/out
-
r
ATP + H2O + H+/in Escherichia coli BW25113
-
ADP + phosphate + H+/out
-
r

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli BW25113
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + H+/in
-
Escherichia coli ADP + phosphate + H+/out
-
r
ATP + H2O + H+/in
-
Escherichia coli BW25113 ADP + phosphate + H+/out
-
r

Synonyms

Synonyms Comment Organism
FoF1-ATPase
-
Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Escherichia coli

pH Range

pH Minimum pH Maximum Comment Organism
5.5 7.5 at pH 7.5 H+ efflux is stimulated in fhlA mutant, with defective transcriptional activator of Hyd-3 or Hyd-4, and lowered in hyaB or hybC mutants, with defective Hyd-1 or Hyd-2. At pH 5.5 H+ efflux in wild-type cells is lowered compared with that at pH 7.5, but is increased in fhlA mutant and absent in hyaB/hybC mutant, overview Escherichia coli