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Literature summary for 7.1.2.1 extracted from

  • Luo, S.; Fang, J.; Docampo, R.
    Molecular characterization of Trypanosoma brucei P-type H+-ATPases (2006), J. Biol. Chem., 281, 21963-21973.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information enzyme depletion by RNAi causes growth inhibition, which is more accentuated in procyclic forms. Knock-down of TbHA1 results in cells with lower steady-state intracellular pH value and a slower rate of intracellular pH value recovery from acidification. Enzyme is functional in Saccharomyces cerevisiae Trypanosoma brucei

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
99500
-
x * 99500, calculated Trypanosoma brucei
100200
-
x * 100200, calculated Trypanosoma brucei
100600
-
x * 100600, calculated Trypanosoma brucei

Organism

Organism UniProt Comment Textmining
Trypanosoma brucei Q6WZI6
-
-
Trypanosoma brucei Q7Z1X2
-
-
Trypanosoma brucei Q86DE0
-
-

Subunits

Subunits Comment Organism
? x * 100200, calculated Trypanosoma brucei
? x * 100600, calculated Trypanosoma brucei
? x * 99500, calculated Trypanosoma brucei

Synonyms

Synonyms Comment Organism
TbHA1
-
Trypanosoma brucei
TbHA2
-
Trypanosoma brucei
TbHA3
-
Trypanosoma brucei

pI Value

Organism Comment pI Value Maximum pI Value
Trypanosoma brucei calculated
-
5.9
Trypanosoma brucei calculated
-
7.3