Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 7.1.1.9 extracted from

  • Ji, H.; Das, T.K.; Puustinen, A.; Wikstroem, M.; Yeh, S.R.; Rousseau, D.L.
    Modulation of the active site conformation by site-directed mutagenesis in cytochrome c oxidase from Paracoccus denitrificans (2010), J. Inorg. Biochem., 104, 318-323.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 7.1.1.9

Protein Variants

Protein Variants Comment Organism
I347Q 16% activity compared to the wild type enzyme Paracoccus denitrificans
R473Q 16% activity compared to the wild type enzyme Paracoccus denitrificans
R474Q 41% activity compared to the wild type enzyme Paracoccus denitrificans
T50A 90% activity compared to the wild type enzyme Paracoccus denitrificans
T50N 50% activity compared to the wild type enzyme Paracoccus denitrificans
V279I 50% activity compared to the wild type enzyme Paracoccus denitrificans
Y339F 64% activity compared to the wild type enzyme Paracoccus denitrificans
Y406F 40% activity compared to the wild type enzyme Paracoccus denitrificans

Metals/Ions

Metals/Ions Comment Organism Structure
copper contains copper Paracoccus denitrificans
Iron contains iron Paracoccus denitrificans

Organism

Organism UniProt Comment Textmining
Paracoccus denitrificans
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oxidized horse heart cytochrome c + H2O
-
 Paracoccus denitrificans reduced horse heart cytochrome c + O2 + H+
-
 ?

Synonyms

Synonyms Comment Organism
CCO
-
 Paracoccus denitrificans
cytochrome c oxidase
-
 Paracoccus denitrificans

Cofactor

Cofactor Comment Organism Structure
heme a
-
 Paracoccus denitrificans
Heme a3
-
 Paracoccus denitrificans